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Paychex HR and Payroll Services in South Carolina

Anyone who’s visited South Carolina knows about Charleston, Myrtle Beach, and Hilton Head. But those who live here know it’s South Carolina businesses that set the state apart. Let Paychex help your business save time with payroll services, HR, and benefits.

Paychex Services for Businesses

Payroll and Taxes

Payroll Services Made Easy for Businesses

Pay employees quickly, easily, and simply by giving employees access to update their own information, automatically processing your payroll tax payments, and getting support whenever you need it from our U.S.-based customer service.

Paychex Flex payroll overview video
Payroll Overview

Work With Our All-in-One PEO To Help Manage HR, Payroll, and Benefits

  • Simplify HR tasks to focus on what matters most
  • Offer Fortune 500-level benefits more affordably
  • Receive guidance on your specific HR issues
A busy office with employee working together
What Is a PEO
Human Resources

Get HR Answers and Guidance From a Knowledgeable HR Professional

Your dedicated Paychex HR professional is available to help you with:

  • Assessing your specific HR needs
  • Personalized and actionable HR guidance based on your needs
  • Finding valuable insights through our leading all-in-one HR technology
HR team welcoming new employee
Workers’ Compensation

Find Compliant Coverage From Top Carriers

South Carolina requires most businesses to carry workers’ compensation insurance. Paychex Insurance Agency can help you find a workers’ comp plan from top-tier national carriers that meets your needs and your budget.

An employee applying for workers' comp

Paychex Flex®: The Single Platform for Your HR, Payroll, and Benefits

Our award-winning Paychex Flex® technology platform combines your HR, payroll, and benefits to help make them all more efficient and easier to manage.

  • Run payroll quickly and easily
  • Access critical reports
  • Let employees update their information
  • Improve HR efficiency

Convenient Service for South Carolina Businesses

From Columbia to Charleston and all the way to Greenville, businesses can contact our service representatives anytime, whenever they have a question or want support.

Employee support column

Contact a Paychex Payroll and HR Consultant

Get the benefit of more than 50 years of experience helping businesses succeed. Let’s talk about how Paychex technology and advisory solutions can help your South Carolina-based business.

hr and payroll customer service representative

Find the Right Solution for Your Business

  • Technology options that grow with your business needs
  • Available guidance from a knowledgeable HR professional
  • Anytime customer service based in the United States
Find Your Solution
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How many employees do you have?

Paychex Is the Smart Choice for Payroll and HR Services

Did you know that Paychex pays 1 in 12 U.S. private-sector employees? That’s 12 million people. We also have more HR professionals helping clients than any other HR solutions company. Thousands of businesses in South Carolina already benefit from our experience. Let’s talk about your business.

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Additional Resources for Businesses in South Carolina

Payroll Solutions for Businesses of Every Size

Paychex Payroll Services can save you and your business time so that you can focus on what matters most. Hear from our customers about why they choose Paychex to help ease the payroll burden.

"StratasCorp Technologies was quickly outgrowing their payroll provider. Paychex helped them save 10 hours a month and $10,000 a year in tax penalties".

“(With staff in multiple states), we had different state labor laws (to deal with) … we didn’t have the resources to address …. Paychex sorted through that for us so we didn’t have to spend any time or effort on figuring it out.”

"Julie [my Paychex HR consultant] does a good job of bringing the best out of us."

“Payroll, HR, keeping up with the changing IRS rules; these are things that are critical to making our business hum … Not having to invest in the back office means we can put our resources into our core business.”

"As a recruitment tool, the 401(k) is a very integral part of what we offer our employees."

Recognized by Industry Experts for Our Innovation, Ethics, and Performance

World's Most Ethical Companies Award 2024
World’s Most Ethical Companies
Customer Satisfaction - IDC SaaS Award
Leader in Customer Satisfaction
FORTUNE World's Most Innovative Companies Award
America’s Most Innovative Companies
Best Small Business-focused solution from HR Tech 2024 award
Best Small Business-Focused Solution
PLANSPONSOR Largest 401(k) Recordkeeper by Number of Plans
Largest 401(k) Recordkeeper
Apex training award winner 2024
World’s Top Training Organizations

Join Our Approximately 740,000 Customers and Get Help Managing HR, Payroll, and Benefits for Your South Carolina Business